Key result
Chemotherapy, long-term oxygen, and anticoagulation therapies effectively treated a 41-year-old woman with pulmonary tumor thrombotic microangiopathy over a 3-month period.
Case Report (n=1)
Antemortem diagnosis of pulmonary tumor thrombotic microangiopathy via transbronchial lung biopsy can allow for effective management with chemotherapy, oxygen, and anticoagulation.
Suggests potential benefit of multimodal therapy after biopsy in PTTM; hypothesis-generating and should not yet change practice.
A 41-year-old woman, who underwent breast resection for cancer of the right breast and adjuvant chemotherapy 2 years ago, was admitted to our hospital due to shortness of breath upon exertion. High-resolution computed tomography of the chest showed small nodular opacities in the peribronchiolar area in both lungs, as well as mediastinal and hilar lymphadenopathy. A transbronchial lung biopsy revealed breast cancer metastasis and pulmonary tumor thrombotic microangiopathy (PTTM). Treatment of PTTM is rarely reported due to the difficulty of antemortem diagnosis; however, the patient was effectively treated with chemotherapy and oxygen and anticoagulation therapies for 3 months.
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Kitamura et al. (2013) conducted a case report in Pulmonary tumor thrombotic microangiopathy (PTTM) (n=1). Chemotherapy, long-term oxygen, and anticoagulation therapies was evaluated on Clinical improvement. Chemotherapy, long-term oxygen, and anticoagulation therapies effectively treated a 41-year-old woman with pulmonary tumor thrombotic microangiopathy over a 3-month period.
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