The stereospecificity of 4 lipases towards enantiomeric alkyldiacylglycerols and alkylmonoacylglycerols was investigated. No stereospecific breakdown of the former substrate was observed for lipases from pancreas,Rhizopus arrhizus, Pseudomonas fluorescens, or bile salt‐stimulated lipase from human milk. All lipases degraded 2‐oleoyl‐3‐tetradecyl‐sn‐glycerol faster than 1‐tetradecyl‐2‐oleoyl‐sn‐glycerol. Among X‐1‐acyl‐3‐alkylglycerol isomers, 1‐acyl‐3‐alkyl‐sn‐glycerol was preferentially attacked by the 3 first mentioned lipases. Possible mechanisms and metabolic implications for these stereospecificities are discussed.
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Åkesson et al. (1983) studied this question.
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