The Acid Phosphatase Content of the Enlarged and Malignant Prostate Gland With Some Observations on Histopathology as Revealed by Gomori's Staining

SUMMARY The glandular acid phosphatase in a series of thirty benign and two cases of malignant enlargement of the prostate was estimated. Wide variation was discovered and the malignant glands were found to contain much less enzyme than the benign. The same glands were stained for acid phosphatase by Gomori's method Acid phosphatase was demonstrated in all. The histology of these sections is described and illustrated. An explanation is submitted for the wide variation in the figures for the benign glands and for the low ones in malignant glands.