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An N ‐formylation method using methanol as the C 1 source without a stoichiometric amount of activating reagent is described. Nitriles as well as amines can be directly used as substrates. The reaction is catalyzed by an N‐heterocyclic carbene coordinated ruthenium(II) dihydride complex, which mediates methanol dehydrogenation, nitrile reduction, and CN bond formation without any external base, hydrogen acceptor, or oxidant. magnified image
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Kang et al. (2015) studied this question.
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