Key result
Enterovirus D68 infection can cause polio-like acute flaccid paralysis and respiratory failure in adults, necessitating specific RT-PCR testing of bronchoalveolar lavage for diagnosis.
Why the study?
Enterovirus D68 (EV-D68) has recently been linked to acute flaccid paralysis particularly in children, but reports of acute neurological and respiratory presentations in young adults are limited.
Case Report (n=1)
No
Enterovirus D68 can cause acute flaccid paralysis and respiratory failure in adults, highlighting the need to consider EV-D68-specific RT-PCR from bronchoalveolar lavage in unexplained cases.
EV-D68 may cause acute neurological symptoms in young adults; leaves open need for surveillance and confirmatory studies.
Enterovirus D68 (EV-D68) is a non-polio enterovirus that occasionally causes respiratory illnesses. EV-D68 infections have occurred over the last couple of years and have a high prevalence worldwide. This virus has recently been linked to acute flaccid paralysis and particularly affects children. We report the case of a young adult who presented with acute neurological manifestations along with respiratory involvement. EV-D68 was detected in the patient's broncho-alveolar lavage and was followed by a prolonged recovery period. Clinicians should consider EV-D68 infection in the differential diagnosis of acute flaccid paralysis (AFP) and respiratory failure.
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Nafisa et al. (2021) conducted a case report in Acute flaccid paralysis and respiratory failure (n=1). Enterovirus D68 infection was evaluated on Clinical outcome. Enterovirus D68 infection can cause polio-like acute flaccid paralysis and respiratory failure in adults, necessitating specific RT-PCR testing of bronchoalveolar lavage for diagnosis.
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