Key result
Cytology-positive pericardial effusion causing tamponade in high-grade serous ovarian carcinoma was managed in three patients, allowing for subsequent chemotherapy treatment.
Patients with cytology-positive pericardial effusion from high-grade serous ovarian carcinoma can be amenable to chemotherapy after symptom improvement.
Pericardial effusions in high-grade serous carcinoma may permit chemotherapy after drainage; hypothesis-generating for post-PARP cases and requires prospective study.
•Three patients with cytology positive pericardial effusions from high grade serous carcinoma.•Patients' conditions amenable to treatment with chemotherapy after effusion symptom improvement.•Patient with pericardial effusion from high grade serous ovarian cancer post a poly ADP ribose polymerase inhibitor.
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Kooy et al. (2020) studied this question. Cytology-positive pericardial effusion causing tamponade in high-grade serous ovarian carcinoma was managed in three patients, allowing for subsequent chemotherapy treatment.
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