Key result
Medium- and long-chain dicarboxyl and hydroxyl acylcarnitines were independently associated with increased carotid-femoral pulse wave velocity (β = 0.24, p = 0.015).
Cross-Sectional (n=141)
Effect estimate: β = 0.24
p-value: p=0.015
Medium- and long-chain dicarboxyl and hydroxyl acylcarnitines are independently associated with arterial stiffness in aged adults without cardiovascular disease, suggesting a role for altered cellular fatty acid oxidation.
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Acylcarnitine factor independently associated with PWV in older adults without CVD; leaves open whether fatty acid oxidation pathways influence stiffness progression.
Koh et al. (2017) conducted a cross-sectional in Aged adults without cardiovascular disease (n=141). Medium- and long-chain dicarboxyl and hydroxyl acylcarnitines was evaluated on Carotid-femoral pulse wave velocity (β = 0.24, p=0.015). Medium- and long-chain dicarboxyl and hydroxyl acylcarnitines were independently associated with increased carotid-femoral pulse wave velocity (β = 0.24, p = 0.015).
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