Key result
Magnesium sulfate infusion reduced post-operative atrial tachyarrhythmias compared to control (10.7% vs 26.7%; p=0.008) in patients undergoing non-cardiac thoracic surgery.
Why the study?
Does magnesium sulfate infusion prevent post-operative atrial tachyarrhythmias in patients undergoing non-cardiac thoracic surgery?
RCT (n=200)
randomly assigned
Does magnesium sulfate infusion prevent post-operative atrial tachyarrhythmias in patients undergoing non-cardiac thoracic surgery?
Magnesium sulfate infusion significantly reduces the incidence of post-operative atrial tachyarrhythmias following non-cardiac thoracic surgery.
Answers are grounded in this paper and cite their sources.
Supports magnesium sulfate prophylaxis for atrial tachyarrhythmias after non-cardiac thoracic surgery; extends perioperative arrhythmia prevention evidence.
The possible role of magnesium sulfate (MgSO4) infusion in the prevention of atrial tachyarrhythmias after non-cardiac thoracic surgery was evaluated through a prospective study of two hundred patients who underwent non-cardiac thoracic surgery. The patients (who fulfilled the following requirements among others: no myocardial infarction in the previous six months, normal renal function, no use of digitalis or antiarrhythmic drugs, not undergone emergency operations or video-assisted thoracic surgery), were randomly assigned to receive MgSO4 infusion in all circumstances (Mg group), or either no treatment or, if aged over 70 or in cases of pneumonectomy or an intrapericardial procedure, application of digoxin starting on the day of operation (control group). 95 patients were enrolled in the Mg group and 105 in the control group. 93 patients in the Mg group and 101 in the control group were evaluated. Post-operative atrial tachyarrhythmias, mainly atrial fibrillation, occurred in 10 patients (10.7%) in the Mg group and in 27 (26.7%) patients in the control group (chi 2 = 7.009, df = 1. p = 0.008). It is concluded that infusion of MgSO4 is an effective means of reducing the incidence of atrial tachyarrhythmias after non-cardiac thoracic surgery.
No takes yet. Share an insight, caveat, or question.
Terzi et al. (1996) conducted an RCT in Non-cardiac thoracic surgery (n=200). Magnesium sulfate (MgSO4) infusion vs. No treatment or digoxin (if >70 years, pneumonectomy, or intrapericardial procedure) was evaluated on Post-operative atrial tachyarrhythmias (p=0.008). Magnesium sulfate infusion reduced post-operative atrial tachyarrhythmias compared to control (10.7% vs 26.7%; p=0.008) in patients undergoing non-cardiac thoracic surgery.
Synapse has enriched 10 related papers. Consider them for comparative context: