Key result
The Metabolic Score for Visceral Fat (METS-VF) was significantly associated with the prevalence of diabetes mellitus (OR 6.8) and demonstrated high diagnostic accuracy compared to other visceral fat indices.
Why the study?
Visceral fat has significant deleterious effects even at the same body mass index, prompting evaluation of the association between the Metabolic Score for Visceral Fat and diabetes mellitus.
Does the Metabolic Score for Visceral Fat (METS-VF) predict the prevalence of diabetes mellitus compared to other VAT indices?
Cross-Sectional (n=3,445)
Does the Metabolic Score for Visceral Fat (METS-VF) predict the prevalence of diabetes mellitus compared to other VAT indices?
METS-VF is a strong predictor of diabetes mellitus and outperforms other surrogate markers for visceral adipose tissue, suggesting its utility for routine screening.
Answers are grounded in this paper and cite their sources.
METS-VF may refine DM risk stratification beyond BMI; leaves open incremental predictive value in prospective cohorts.
INTRODUCTION: With 42.4% of obese US population, the prevalence of diabetes mellitus (DM) is increasing. Visceral fat, even at the same body mass index, has significant deleterious effects. This study aims to investigate the association between the Metabolic Score for Visceral Fat (METS-VF) and DM. METHODS: The study utilized data from NHANES dataset, covering cycles from 2011 to 2018. Multivariate logistic regression and Receiver Operating Characteristic (ROC) analysis assessed the association between METS-VF and DM. Additionally, the study compared visceral adipose tissue (VAT) measurement indices to METS-VF for the prediction of DM. RESULTS: In 3,445 participants, METS-VF was positively associated with diabetes [(OR 6.8; 95% CI 5.3-8.6) (AUC 0.791; 95% CI 0.768-0.814)], the association increased across quartiles (METS-VF >6.5; OR 53.8; 95% CI 0.17-169).METS-VF significantly identifies diabetes compared to other VAT indices (LAP, VAI, waist circumference, and WHtR). Additionally premenopausal females with BMI >25 and METS-VF >6.5 are at a higher risk of developing diabetes. CONCLUSION: METS-VF positively associates with the prevalence of diabetes. It is an effective score compared to surrogate markers for VAT measurement. Routine screening of VAT using METS-VF score could be implemented in daily clinical settings and large-scale epidemiological studies to help identify early diabetes.
No takes yet. Share an insight, caveat, or question.
Tripathi et al. (2025) conducted a cross-sectional in Diabetes mellitus (n=3,445). Metabolic Score for Visceral Fat (METS-VF) vs. Lower METS-VF scores was evaluated on Prevalence of diabetes mellitus (OR 6.8, 95% CI 5.3-8.6, p=0.001). The Metabolic Score for Visceral Fat (METS-VF) was significantly associated with the prevalence of diabetes mellitus (OR 6.8) and demonstrated high diagnostic accuracy compared to other visceral fat indices.
Synapse has enriched 10 related papers. Consider them for comparative context: