A variant of lactate dehydrogenase in somatic tissues of pigeons: Physicochemical properties and genetic control

This is the authors' abstract. We don't add key points for this paper.

Three genetic loci (a, b, and c) control lactate dehydrogenase synthesis in many mammalian and avian species. A survey of the lactate dehydrogenase isozyme composition of somatic tissues from approximately 1,000 wild pigeons revealed three phenotypic classes. The frequency distribution of the three classes in wild pigeons and the results of appropriate breeding experiments demonstrated that the phenotypic differences were due to alleles at the b‐locus. One of the alleles produces a B' polypeptide with an electrophoretic mobility identical to that of the A polypeptide, but with substrate affinity and heat inactivation properties similar to those of the B polypeptide.