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March 27, 2008Journal of Clinical MicrobiologyOpen Access

Rapid Detection of the Mosaic Structure of the Neisseria gonorrhoeae penA Gene, Which Is Associated with Decreased Susceptibilities to Oral Cephalosporins

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Authors

SOSusumu OchiaiNational Institute for Biological Standards and ControlHIHiroaki IshikoMitsubishi Chemical (Japan)MYMitsuru YasudaSapporo Medical University

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Ochiai et al. (2008) studied this question.

synapsesocial.com/papers/6a9570dbabd4c05a5bf5a33bhttps://doi.org/10.1128/jcm.01800-07
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Emergence and Spread of <i>Neisseria gonorrhoeae</i> Clinical Isolates Harboring Mosaic-Like Structure of Penicillin-Binding Protein 2 in Central Japan2004 · 208 citations
  2. 2Diversity of <i>penA</i> Alterations and Subtypes in <i>Neisseria gonorrhoeae</i> Strains from Sydney, Australia, That Are Less Susceptible to Ceftriaxone2007 · 124 citations
  3. 3Decreased affinity of mosaic-structure recombinant penicillin-binding protein 2 for oral cephalosporins in Neisseria gonorrhoeae2007 · 38 citations
  4. 4Genetics of resistance in a non-beta-lactamase-producing gonococcus with relatively high-level penicillin resistance1986 · 62 citations
  5. 5Amino Acid Substitutions in Mosaic Penicillin-Binding Protein 2 Associated with Reduced Susceptibility to Cefixime in Clinical Isolates of <i>Neisseria gonorrhoeae</i>2006 · 121 citations