Immunosuppressive Drug Therapy as a Potentiator of Skin Tumours in Five Patients With Lymphoma

In four cases of stage 1 chronic lymphatic leukaemia and one of well-differentiated, lymphosarcoma confined to the head and neck regions, the use of immunosuppressive drugs has potentiated in an actinically damaged skin the production of florid BCC, SCC and malignant melanoma. As of now no metastases have occurred in the four survivors. A case of Gorlin's syndrome and lymphatic leukaemia has failed to respond to topical 5 flurouracil therapy, whilst under the influence of chlorambucil therapy.