Key result
The prevalence rate of chronic kidney disease among patients with type 2 diabetes mellitus in Hungary decreased significantly from 9.8% in 2016 to 6.5% in 2020, suggesting under-recognition and under-reporting.
Why the study?
Recognition of chronic kidney disease is crucial in type 2 diabetes mellitus, prompting an evaluation of T2DM-associated CKD in Hungary.
Observational (n=670,559)
Absolute Event Rate: 6.5% vs 9.8%
p-value: p=<0.001
The reported prevalence of CKD in Hungarian patients with T2DM is low and decreasing, suggesting significant under-recognition and under-reporting in clinical practice.
Reported CKD decline in T2DM cautions against under-recognition in practice; leaves open validation of true prevalence in observational cohorts.
Objectives: Recognition of chronic kidney disease (CKD) is crucial in type 2 diabetes mellitus (T2DM). We conducted a nationwide epidemiological study to evaluate T2DM-associated CKD in Hungary between 2016 and 2020. Methods: Annual incidence and prevalence rates of registered CKD amongst all pharmacologically treated T2DM patients were analyzed in different age-groups by the central database of the Hungarian Health Insurance Fund Management. Statistical methods included Poisson regression, Bonferroni test, Chi-square test. Results: We found 499,029 T2DM patients and 48,902 CKD patients in 2016, and 586,075 T2DM patients and 38,347 CKD patients in 2020. The majority of all prevalent T2DM and CKD patients were older (aged 60–69 years: 34.1% and 25.8%; ≥70 years: 36.1% and 64.4%, respectively). The annual incidence of T2DM and incidence rates of CKD in T2DM decreased in 2017–2020 (p < 0.001). The annual prevalence of T2DM increased (p < 0.01), the prevalence rates of CKD in T2DM were low and decreased from 9.8% to 6.5% in 2016–2020 (p < 0.001). Conclusion: Incidence and prevalence of T2DM-associated CKD decreased significantly in Hungary in 2016–2020. Lower prevalence rates of CKD may suggest under-recognition and/or under-reporting.
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Ladányi et al. (2023) conducted an observational in Type 2 diabetes mellitus and chronic kidney disease (n=670,559). Pharmacologically treated type 2 diabetes mellitus was evaluated on Prevalence rate of CKD in T2DM (p=<0.001). The prevalence rate of chronic kidney disease among patients with type 2 diabetes mellitus in Hungary decreased significantly from 9.8% in 2016 to 6.5% in 2020, suggesting under-recognition and under-reporting.
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