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In transdermal drug delivery, the property of protecting barriers of the skin plays a role of major issue as skin does not allow passing the drug. The complex structure of skin is responsible for this issue. The present review was based on the recent updates on transdermal patches. An additional method of administering medications through the skin layer is transdermal drug delivery. A transdermal patch is a medicated patch that can be applied topically to provide medication at a specified rate directly into the bloodstream via the layers of skin. Actually, the most practical way to administer is via patches. In general, there are four main types of transdermal medical patches (drug-in adhesive, reservoir, matrix, and micro-reservoir systems). It concluded that transdermal patches hold promise as a convenient and efficient drug delivery method for a range of conditions; however, there are a number of obstacles that need to be addressed. These include the potential for self-inflicted toxicity due to incorrect dosing, poor adhesion, low drug penetration, potential trigger for skin irritation, or patch failure. In order to maximise the safety and effectiveness of this delivery system, all of this calls for additional study and development.
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Chaturvedi et al. (2024) studied this question.
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