Key result
Exogenous estrogen therapy in transgender women is associated with an increased risk of insufficiency fractures and thromboembolism.
Why the study?
Orthopaedic care providers desire to care for transgender patients but report a self-perceived knowledge deficit, and the impact of gender-affirming care on athletic injuries is less well studied.
Medical and surgical gender-affirming care, particularly exogenous estrogen therapy, can impact musculoskeletal physiology and increase the risk of insufficiency fractures and thromboembolism in transgender athletes.
May prompt orthopaedic education on transgender athletes; leaves open musculoskeletal effects of gender-affirming care for prospective study.
Orthopaedic surgeons and other orthopaedic care providers have expressed a desire to care for transgender patients but have a self-perceived knowledge deficit. Transgender athletes experience many psychosocial barriers to sport that are useful for clinicians to understand. Medical and surgical gender-affirming care can impact musculoskeletal physiology and pathophysiology. Transgender women (TW) have demonstrated an increased risk of insufficiency fractures and thromboembolism in patients receiving exogenous estrogen therapy. The impact of gender-affirming care on sex-based differences in athletic injuries is less well studied.
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McGovern et al. (2023) conducted a review in Transgender athletes. Exogenous estrogen therapy was evaluated. Exogenous estrogen therapy in transgender women is associated with an increased risk of insufficiency fractures and thromboembolism.
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