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An alcoholic extract of freshly collected Eclipta alba exhibited dose‐dependent (62.5–500.0 mg/kg p.o.) significant hepatoprotective activity against carbon tetrachloride‐induced liver injury in rats and mice. It indicated its protective role on parameters such as hexobarbitone‐induced sleep, zoxazolamine‐induced paralysis, bromosulphalen (BSP) clearance, serum levels of transaminases, bilirubin and protein. The extract did not show any signs of toxicity and the minimum lethal dose was greater than 2.0 g/kg when given orally and intraperitoneally in mice.
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Singh et al. (1993) studied this question.
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