Key result
This review describes mechanisms of norovirus transmission, available model systems for studying transmission, and future research strategies.
This review summarizes current knowledge on norovirus transmission mechanisms and model systems to aid in developing tailored outbreak prevention and control strategies.
May refine tailored norovirus outbreak controls; leaves open identification of actionable determinants for validation.
Human norovirus is a leading cause of gastroenteritis and is efficiently transmitted between humans and around the globe. The burden of norovirus infections in the global community and in health-care settings warrant the availability of outbreak prevention strategies and control measures that are tailored to the pathogen, outbreak setting and population at risk. A better understanding of viral and host determinants of transmission would aid in developing and fine-tuning such efforts. Here, we describe mechanisms of transmission, available model systems for studying norovirus transmission and their strengths and weaknesses as well as future research strategies.
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Graaf et al. (2017) conducted a review in Norovirus infection. This review describes mechanisms of norovirus transmission, available model systems for studying transmission, and future research strategies.
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