Key result
Screening with dipstick proteinuria underestimated chronic kidney disease risk compared to dipstick albumin-to-creatinine ratio, reclassifying 37.2% of subjects with at least moderately increased risk into lower risk categories.
Why the study?
Chronic kidney disease needs to be detected early to prevent poor outcomes, and dipstick tests can now simultaneously assess urinary albumin-to-creatinine ratio and proteinuria.
Does dipstick ACR improve detection of CKD compared to dipstick proteinuria in a primary healthcare setting?
Cross-Sectional (n=88,478)
Yes
Does dipstick ACR improve detection of CKD compared to dipstick proteinuria in a primary healthcare setting?
Absolute Event Rate: 16.3% vs 12.7%
ACR dipstick may better detect CKD risk than proteinuria; leaves open outcome impact in primary care.
Chronic kidney disease (CKD) needs to be detected early in order to prevent a poor outcome in the general population. A semiquantitative evaluation based on a dipstick has become available to detect the urinary albumin-to-creatinine ratio (ACR) and proteinuria simultaneously in spot urine samples. The aim of this study was to compare dipstick ACR with proteinuria for CKD screening in a primary healthcare setting.
No takes yet. Share an insight, caveat, or question.
Nah et al. (2021) conducted a cross-sectional in Chronic Kidney Disease (n=88,478). Dipstick albumin-to-creatinine ratio (ACR) vs. Dipstick proteinuria was evaluated on Prevalence of Chronic Kidney Disease (CKD). Screening with dipstick proteinuria underestimated chronic kidney disease risk compared to dipstick albumin-to-creatinine ratio, reclassifying 37.2% of subjects with at least moderately increased risk into lower risk categories.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: