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Leukotriene B4, but not leukotrienes C4, D4, E4, or 12(S)-leukotriene B4, inhibited in a concentration-dependent manner the capacity of PHA-stimulated human T lymphocytes to generate LIF activity and to proliferate, as assessed by the uptake of [3H]thymidine.
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Payan et al. (1983) studied this question.
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