SUMMARY A concentration of 11.5 mg of vitamin E per reconstituted quart of Alacta was insufficient to prevent uniformly the development of vitamin E-responsive anemia in four premature infants. This was possibly due to poor absorption of the vitamin E. In this study, in addition to the hemolysis reversal, vitamin E administration appeared to increase total serum proteins and to decrease methylmalonate excretion.
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Barness et al. (1968) studied this question.
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