Key result
Coil embolization of septal branches successfully reduced the resting left ventricular outflow tract pressure gradient from 73 mmHg to 30 mmHg in a patient with hypertrophic obstructive cardiomyopathy.
Why the study?
Does coil embolization of septal branches reduce the LVOT pressure gradient in a patient with HOCM?
Case Report (n=1)
Does coil embolization of septal branches reduce the LVOT pressure gradient in a patient with HOCM?
Coil embolization of septal branches successfully reduced the LVOT pressure gradient in a patient with HOCM, suggesting a potential alternative to alcohol septal ablation.
Hypothesis-generating for coil embolization in HOCM; larger prospective trials needed before clinical adoption.
Hypertrophic cardiomyopathy (HCM) has been associated with sudden death in young athletes. On long-term follow up, syncope, chest pain and dyspnea are well known frequent symptoms due to the dynamic left ventricular outflow tract (LVOT) obstruction, mitral regurgitation and diastolic dysfunction. To reduce the LVOT pressure gradient, septal myectomy and alcohol injection have recently been utilized. However, some complications have been reported with alcohol ablation of the septal branches, such as complete atrioventricular block and alcohol spill over to ablate the entire left anterior descending coronary artery. Herein, a case of coil embolization of the septal branches, with successful reduction of the LVOT pressure gradient, is reported in a patient with HOCM.
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Song et al. (2004) conducted a case report in Hypertrophic Obstructive Cardiomyopathy (n=1). Coil embolization of septal branches was evaluated on Left ventricular outflow tract (LVOT) pressure gradient. Coil embolization of septal branches successfully reduced the resting left ventricular outflow tract pressure gradient from 73 mmHg to 30 mmHg in a patient with hypertrophic obstructive cardiomyopathy.
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