Pre-operative beta-blockade may not fully mitigate the risk of thyroid storm and subsequent severe heart failure during thyroidectomy in thyrotoxic patients.
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May not prevent severe post-thyroidectomy heart failure despite beta-blockade; leaves open optimal perioperative strategies in thyrotoxic patients.
A thyrotoxic patient who had received beta-adrenoceptor blockers pre-operatively suffered an episode of severe heart failure immediately following thyroidectomy and required artificial ventilation of the lungs for six hours. The possible causes are discussed and the likelihood of thyroid storm unmitigated by beta adrenergic blockade suggested.
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Patrick Strube (1984) studied this question.
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