Hypothalamic‐pituitary‐gonadal function was investigated in a group of 13 actively drinking chronic alcoholics. In a high proportion (46 per cent) of the patients basal plasma luteinising hormone (LH) levels were elevated and these patients showed an exaggerated plasma LH response to 100 μg LHRF. Plasma levels of 17β‐hydroxy‐androgens were normal in all subjects. Liver damage did not appear to explain the biochemical findings which may, however, be relevant to sexual and reproductive function in chronic alcoholic patients.
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Wright et al. (1976) studied this question.
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