Key result
Double-valve replacement for aortic valve disease with moderate mitral regurgitation yielded 5-year survival and quality of life similar to patients without mitral insufficiency.
Why the study?
Does double-valve replacement improve long-term outcomes compared to aortic valve replacement alone in patients with aortic valve disease and concomitant moderate mitral regurgitation?
Cohort (n=71)
Does double-valve replacement improve long-term outcomes compared to aortic valve replacement alone in patients with aortic valve disease and concomitant moderate mitral regurgitation?
Double-valve replacement may be advisable for patients with aortic valve disease and moderate functional mitral regurgitation, as leaving the mitral valve untreated leads to persistent MR and worse long-term survival.
AIM: To analyze long-term surgical results in patients with aortic valve disease and concomitant mitral regurgitation (MR) depending on volume of valve surgery. MATERIAL AND METHODS: It was studied 5-year results in 71 patients with aortic valve disease and different degree of mitral regurgitation. Patients were divided into 3 groups. Control group included 40 patients after aortic valve replacement (AVR) and no mitral insufficiency. The 2nd group consisted of 16 patients after AVR and concomitant mitral regurgitation degree 2-3. The 3rd group - 15 patients after aortic and mitral valve replacement. Mortality in long-term postoperative period, quality of life, incidence of complications and echocardiography data were analyzed. RESULTS: There was no significant improvement of mitral regurgitation after AVR. It was showed that persistent MR decreases remote survival and quality of life as well as deteriorates echocardiography data. Herewith these data in the 3rd group did not differ from the control group. CONCLUSION: Double-valve replacement may be advisable in patients with aortic valve disease and concomitant moderate MR because persistent MR deteriorates long-term RESULTS: However prolonged time of cardiopulmonary bypass, aortic cross-clamping, greater blood loss require comprehensive approach to advanced cardiac surgery.
No takes yet. Share an insight, caveat, or question.
Salagaev et al. (2016) conducted a cohort in Aortic valve disease and functional mitral insufficiency (n=71). Double-valve replacement (aortic and mitral) vs. Aortic valve replacement alone was evaluated on Mortality in long-term postoperative period, quality of life, incidence of complications and echocardiography data. Double-valve replacement for aortic valve disease with moderate mitral regurgitation yielded 5-year survival and quality of life similar to patients without mitral insufficiency.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: