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March 1, 2011Journal of Cardiothoracic SurgeryOpen Access

A comparative study of four intensive care outcome prediction models in cardiac surgery patients

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Why the study?

Do CASUS and SOFA provide better ICU mortality risk stratification than SAPS II and APACHE II in cardiac surgery patients?

Population

2,801 consecutive adult patients who underwent open heart surgery and were admitted to the intensive care…

Design

Cohort

Follow-up

Until ICU discharge (mean ICU length of stay 4.3 days)

Authors

FDFabian DoerrRuhrlandklinikABAkmal M.A. BadreldinKlinikum KasselMHMatthias HeldweinUniversity of Cologne

Discussion

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Implication

May support CASUS/SOFA for ICU mortality prediction after cardiac surgery; leaves open need for prospective validation before practice change.

Structured PICO

Do CASUS and SOFA provide better ICU mortality risk stratification than SAPS II and APACHE II in cardiac surgery patients?

P
Population
2,801 consecutive adult patients who underwent open heart surgery and were admitted to the intensive care unit (ICU), mean age 66.9, 29.6% female, single-center in Germany.
I
Intervention
Application of four intensive care outcome prediction scoring systems (CASUS, SOFA, SAPS II, and APACHE II) calculated daily from ICU admission until discharge.
O
Outcome
ICU mortalityhard clinical

CASUS and SOFA are reliable ICU mortality risk stratification models for cardiac surgery patients, whereas the general SAPS II and APACHE II scores perform poorly in this specific population.

Limitations

  • Single-center study
  • Severe decrease in study population by the third day due to transfer of uncomplicated cases
  • Lack of external multicenter validation for CASUS

Cite This Study

Doerr et al. (2011) studied this question.

synapsesocial.com/papers/6a9591042273404a50fa6ea7https://doi.org/10.1186/1749-8090-6-21
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1SAPS 3—From evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission2005 · 1,458 citations
  2. 2Risk stratification for adverse outcome in cardiac surgery2003 · 48 citations
  3. 3Risk stratification for adverse outcome in cardiac surgery2005 · 41 citations
  4. 4Serial Evaluation of the SOFA Score to Predict Outcome in Critically Ill Patients2001 · 2,960 citations
  5. 5Severity scoring in the ICU: a review2008 · 181 citations