Key result
Metabolic syndrome was associated with significantly higher NTproBNP levels compared to metabolically healthy controls (mean difference -404.68, p<0.001).
Why the study?
The study was conducted to evaluate the association between NTproBNP values and various biochemical and anthropometric parameters in metabolic syndrome patients compared with non-metabolic syndrome individuals.
Are NT-proBNP levels associated with metabolic syndrome and its components in adults without heart failure?
Case-Control (n=200)
No
Are NT-proBNP levels associated with metabolic syndrome and its components in adults without heart failure?
NT-proBNP levels are significantly elevated in patients with metabolic syndrome without heart failure and correlate positively with metabolic parameters such as triglycerides.
Answers are grounded in this paper and cite their sources.
May indicate subclinical cardiac strain in metabolic syndrome; hypothesis-generating and should not yet change practice.
Aim: The association between NTpro BNP values and different biochemical and anthropometric parameters of metabolic syndrome patients and non-metabolic syndrome individuals are correlated here. Methods: The research involved 200 people aged 21 to 60 years old (100 control and 100 cases). The following measurements were taken- FBS, SBP, DBP, BMI, and lipid profile. Using multiple regression, we examined the correlation between NTproBNP and metabolic syndrome and non-metabolic syndrome patients. Correlation of Metabolic syndrome parameters with NTproBNP values are done. Result: NT pro BNP values are higher in metabolic syndrome patients in comparison to non-Metabolic syndrome patients. NTproBNP values are positively correlated with SBP, TG, LDL values in metabolic syndrome patients. Conclusion: NT pro BNP values are higher in metabolic syndrome patients in comparison to non-Metabolic syndrome patients.
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Dash et al. (2022) conducted a case-control in Metabolic syndrome (n=200). Metabolic syndrome vs. Non-metabolic syndrome was evaluated on NTproBNP levels (MD -404.68, 95% CI -412.508 to -396.852, p=<0.001). Metabolic syndrome was associated with significantly higher NTproBNP levels compared to metabolically healthy controls (mean difference -404.68, p<0.001).
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