Key result
A higher Clinical Frailty Score was an independent risk factor for one-year mortality in elderly patients after elective orthopedic surgery (OR 2.271).
Why the study?
Frailty is associated with perioperative adverse outcomes in the elderly, but whether it independently predicts one-year mortality after elective orthopedic surgery remained to be assessed.
Does frailty increase one-year mortality in elderly patients undergoing elective orthopedic surgery?
Cohort (n=313)
No
Does frailty increase one-year mortality in elderly patients undergoing elective orthopedic surgery?
Odds Ratio: 2.271 (95% CI 1.472–3.504)
p-value: p=<0.001
Preoperative frailty assessment using the Clinical Frailty Score independently predicts one-year mortality in elderly patients undergoing elective orthopedic surgery.
Supports preoperative frailty assessment in elderly orthopedic patients; leaves open whether modifying frailty alters mortality.
Frailty is associated with perioperative adverse outcomes, especially for the elderly. This study aimed to assess whether frailty was an independent risk factor of one-year mortality in frail patients after elective orthopedic surgery. In this prospective study, three hundred and thirteen patients aged ≥ 65 years, undergoing elective orthopedic surgery were finally included. Frailty assessed by the Clinical Frailty Score (CFS) before the surgery was present in 29.7% (93/313). Among them, 7.7% of patients (24/313) died at one year after surgery. In multivariate logistic analysis, higher CFS (OR = 2.271, 95% CI= 1.472-3.504) was found to be an independent risk factor of one-year mortality after surgery in elderly orthopedic patients. The area under the receiver operating characteristic curve of the model was 0.897 (95% CI 0.834-0.959). In addition, we found higher Charlson comorbidity index (OR= 1.498, 95% CI = 1.082-2.073) was also a significant risk factor. In conclusion, frailty is associated with increased one-year mortality in elderly patients after elective orthopedic surgery, which should be considered as a routine assessment tool in preoperative practice.
No takes yet. Share an insight, caveat, or question.
Sun et al. (2021) conducted a cohort in Elective orthopedic surgery in elderly patients (n=313). Higher Clinical Frailty Score (CFS) vs. Lower Clinical Frailty Score was evaluated on One-year mortality (OR 2.271, 95% CI 1.472-3.504, p=<0.001). A higher Clinical Frailty Score was an independent risk factor for one-year mortality in elderly patients after elective orthopedic surgery (OR 2.271).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: