Key result
A high Hip-Multidimensional Frailty Score (>8) was associated with a significantly increased risk of 6-month mortality compared to a low score (≤8) in elderly patients after hip fracture surgery (HR 3.545).
Why the study?
Does the Hip-Multidimensional Frailty Score (Hip-MFS) predict 6-month mortality and postoperative complications in elderly patients with hip fracture?
Cohort (n=481)
No
Does the Hip-Multidimensional Frailty Score (Hip-MFS) predict 6-month mortality and postoperative complications in elderly patients with hip fracture?
Hazard Ratio: 3.545 (95% CI 1.466–8.572)
Absolute Event Rate: 18.8% vs 3.6%
p-value: p=<0.001
The Hip-Multidimensional Frailty Score (Hip-MFS) is a valid tool that predicts 6-month mortality and postoperative complications more accurately than conventional risk factors in elderly patients undergoing hip fracture surgery.
May aid postoperative risk stratification in elderly hip fracture patients; leaves open prospective validation before clinical adoption.
High mortality and dependent living after hip fracture pose a significant public health concern. Retrospective study was conducted with 481 hip fracture patients (≥65 years of age) undergoing surgery from March 2009 to May 2014. The Hip-MFS was calculated by Comprehensive Geriatric Assessment (CGA). The primary outcome was the 6-month all-cause mortality rate. The secondary outcomes were 1-year all-cause mortality, postoperative complications and prolonged hospital stay, and institutionalization. Thirty-five patients (7.3%) died within 6 months after surgery (median [interquartile range], 2.9 [1.4-3.9] months). The fully adjusted hazard ratio per 1 point increase in Hip-MFS was 1.458 (95% confidence interval [CI]: 1.210-1.758) for 6-months mortality and odds ratio were 1.239 (95% CI: 1.115-1.377), 1.156 (95% CI: 1.031-1.296) for postoperative complications and prolonged total hospital stay, respectively. High-risk patients (Hip-MFS > 8) showed higher risk of 6-month mortality (hazard ratio: 3.545, 95% CI: 1.466-8.572) than low-risk patients after adjustment. Hip-MFS successfully predict 6-month mortality, postoperative complications and prolonged hospital stay in elderly hip fracture patients after surgery. Hip-MFS more precisely predict 6-month mortality than age or existing tools (P values of comparison of ROC curve: 0.002, 0.004, and 0.044 for the ASA classification, age and NHFS, respectively).
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Choi et al. (2017) conducted a cohort in Hip fracture (n=481). High Hip-Multidimensional Frailty Score (Hip-MFS > 8) vs. Low Hip-Multidimensional Frailty Score (Hip-MFS ≤ 8) was evaluated on 6-month all-cause mortality (HR 3.545, 95% CI 1.466-8.572, p=<0.001). A high Hip-Multidimensional Frailty Score (>8) was associated with a significantly increased risk of 6-month mortality compared to a low score (≤8) in elderly patients after hip fracture surgery (HR 3.545).
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