Key result
Computed tomography measurement of the mitral valve in dogs without heart disease demonstrated excellent interobserver agreement with intraclass correlations greater than 0.9.
Why the study?
The study was conducted to measure the mitral annulus in dogs, hypothesizing that CT measurements would be possible and consistent among observers.
Cross-Sectional (n=233)
CT provides a reliable and consistent method for measuring the mitral annulus in dogs, which may aid in developing future treatments for mitral valve dysfunction.
Supports reproducible CT mitral annulus assessment in dogs; leaves open translation to clinical interventions.
OBJECTIVE: To measure the mitral annulus in dogs. Our hypothesis was that mitral measurement would be possible and consistent among observers using CT. SAMPLE: Thoracic CT scans of dogs without known heart disease. PROCEDURES: Five trained investigators measured 4 aspects of the mitral valve and the fourth thoracic vertebrae (T4) length using multiplanar reformatting tools. Ten randomly chosen animals were measured by all investigators to determine interobserver reliability. RESULTS: There were 233 CT scans eligible for inclusion. Dogs weighed 2 to 96 kg (mean, 28.1 kg), with a variety of breeds represented. Golden Retrievers (n = 28) and Labrador Retrievers (n = 37) were overrepresented. The intraclass correlations were all greater than 0.9, showing excellent agreement between observers. The means and SDs of each measurement were as follows: trigone-to-trigone distance, 17.2 ± 4.7 mm; the remaining circumference, 79.0 ± 17.5 mm; commissure-to-commissure distance, 30.8 ± 6.5 mm; septal leaflet-to-lateral leaflet distance, 26.3 ± 6.0 mm; T4 length, 16.9 ± 3.1 mm; and the total circumference normalized by T4, 5.7 ± 0.7 mm. CLINICAL RELEVANCE: This study provides information that may help in the development of future treatment for mitral valve dysfunction and subsequent annular enlargement.
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Gordon‐Evans et al. (2022) conducted a cross-sectional in Dogs without known heart disease (n=233). Computed tomography was evaluated on Interobserver reliability and mitral valve measurements. Computed tomography measurement of the mitral valve in dogs without heart disease demonstrated excellent interobserver agreement with intraclass correlations greater than 0.9.
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