Case report demonstrates multimodal treatment of ruptured polymicrobial brain abscess in a 57-year-old male, highlighting adjuvant intraventricular antimicrobials.
The authors present the case of a 57-year-old male with a large polymicrobial brain abscess complicated by eruption into the intraventricular space. He was treated with parenteral ampicillin, cefepime, and metronidazole and adjuvant intraventricular vancomycin/gentamicin as well as surgical debridement. The authors discuss the diagnosis, treatment, and prognosis of brain abscesses, with a focus on prior cases with pyogenic ventriculitis and those treated with intraventricular antimicrobials.
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Feinberg et al. (2022) studied this question.
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