Decreased heart rate variability as a predictor for diabetes—A prospective study of the Brazilian longitudinal study of adult health
Key result
Low heart rate variability was associated with an increased risk of developing diabetes over 4 years, with low SDNN increasing risk by 29% (RR 1.29; 95% CI 1.09-1.52; P=0.003).
Why the study?
It was investigated whether heart rate variability acts as a predictor for incident diabetes over 4 years of follow-up.
Does decreased heart rate variability predict the incidence of diabetes in adults free of diabetes?
Population
9192 participants free of diabetes
Comparison
HRV lower than the 25th percentile vs 25th to 75th percentiles vs higher than 75th percentile
Design
Prospective cohort study
Follow-up
4 years
Authors
Discussion
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Member takes
Implication
Supports autonomic dysfunction as diabetes risk factor; hypothesis-generating and should not yet change practice.
Study Design
Type
Cohort (n=9,192)
Structured PICO
Does decreased heart rate variability predict the incidence of diabetes in adults free of diabetes?
P
Population
9,192 participants free of diabetes followed for 4 years to assess the incidence of diabetes.
E
Exposure
Decreased heart rate variability (HRV) (lower than the 25th percentile for age-specific value distributions)
C
Comparator
Higher heart rate variability (between the 25th and 75th percentiles, and higher than the 75th percentile)
O
Outcome
Incidence of diabetes at 4-year follow-uphard clinical
Main Result
Relative Risk: 1.29 (95% CI 1.09–1.52)
p-value: p=0.003
Decreased heart rate variability is an independent risk predictor for the incidence of diabetes over a 4-year period in adults initially free of the disease.
Cite This Study
Hoshi et al. (2019) conducted a cohort in Diabetes (n=9,192). Low heart rate variability vs. Higher heart rate variability was evaluated on Incidence of diabetes (RR 1.29, 95% CI 1.09-1.52, p=0.003). Low heart rate variability was associated with an increased risk of developing diabetes over 4 years, with low SDNN increasing risk by 29% (RR 1.29; 95% CI 1.09-1.52; P=0.003).