Key result
Traditional Chinese medicine formulations show potential in treating type 2 diabetes mellitus and its hepatic complications by improving insulin resistance, inflammation, and oxidative stress.
Why the study?
To summarize the common pathogenic mechanism of T2DM and NAFLD, IR and its concomitant factors, and the status of traditional Chinese medicine compound therapy to provide a theoretical basis for clinical treatment.
This review highlights the interconnected mechanisms of insulin resistance, inflammation, and oxidative stress in T2DM and NAFLD, and outlines the potential multi-target benefits of traditional Chinese medicine.
Type 2 diabetes (T2DM) is the most common form of diabetes and is a heterogeneous disease that is typically associated with compensatory insulin secretion impairment and insulin resistance. Insulin resistance (IR) is a common pathological feature of metabolic diseases, including obesity, non-alcoholic fatty liver disease (NAFLD), and T2DM, which can reduce the metabolic response of target cells to insulin, leading to impaired ability of circulating or injected insulin to lower blood glucose levels at the whole-body level. This review summarizes the common pathogenic mechanism of T2DM and NAFLD, IR and its concomitant factors, and the current status of traditional Chinese medicine compound therapy, providing a theoretical basis for clinical medicine treatment.
No takes yet. Share an insight, caveat, or question.
Liu et al. (2023) conducted a review in Type 2 diabetes mellitus and non-alcoholic fatty liver disease. Traditional Chinese Medicine formulations was evaluated. Traditional Chinese medicine formulations show potential in treating type 2 diabetes mellitus and its hepatic complications by improving insulin resistance, inflammation, and oxidative stress.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: