Key result
Acute biliary pancreatitis was associated with significantly prolonged TpTe intervals compared to healthy controls (88.13 ms vs 81.97 ms, p=0.022).
Why the study?
Cardiovascular involvement is a multisystemic manifestation of acute biliary pancreatitis, but how the predictive electrocardiographic Tpeak-Tend interval is affected had not been previously examined.
Are the Tpeak-Tend (TpTe) and QTc intervals prolonged in patients with acute biliary pancreatitis compared to healthy controls?
Case-Control (n=68)
No
Are the Tpeak-Tend (TpTe) and QTc intervals prolonged in patients with acute biliary pancreatitis compared to healthy controls?
Absolute Event Rate: 88.13% vs 81.97%
p-value: p=0.022
Acute biliary pancreatitis is associated with prolonged TpTe and QTc intervals, which may indicate an increased risk of ventricular arrhythmias.
TpTe prolongation in acute biliary pancreatitis may flag arrhythmia risk; hypothesis-generating and needs prospective validation.
Introduction: Cardiovascular involvement is one of the multisystemic manifestations of acute biliary pancreatitis. In this study, we aimed to examine, to our knowledge, for the first time, how the Tpeak-Tend (TpTe) interval, a highly predictive electrocardiographic marker, is affected in patients with acute biliary pancreatitis. Methods: A total of 68 subjects were recruited in this retrospective case-control study. To determine the Corrected QT Intervals (QTc) and TpTe intervals, the electrocardiographs of all subjects were manually examined using the precordial V5 lead. Results: We found that the TpTe and QTc intervals were longer in the cases compared to the controls, and this difference was statistically significant (p<0.05). With respect to acute biliary pancreatitis, the QTc had 68.4% sensitivity and 67% specificity (AUC=0.660, CI: 0.529-0.791; p=0.024) and the TpTe interval had 76.3% sensitivity and 63.3% specificity (AUC=0.647, CI: 0.508-0.787; p=0.038).
No takes yet. Share an insight, caveat, or question.
Abdullah Algın (2020) conducted a case-control in Acute biliary pancreatitis (n=68). Acute biliary pancreatitis vs. Healthy controls was evaluated on TpTe interval (p=0.022). Acute biliary pancreatitis was associated with significantly prolonged TpTe intervals compared to healthy controls (88.13 ms vs 81.97 ms, p=0.022).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: