Key result
Lateral early repolarization was the most frequent electrocardiographic finding in acute pancreatitis and significantly correlated with disease severity as measured by the Ranson score (p = 0.005).
Why the study?
Do early repolarization changes on electrocardiography correlate with disease severity in patients with acute pancreatitis?
Observational (n=55)
Do early repolarization changes on electrocardiography correlate with disease severity in patients with acute pancreatitis?
p-value: p=0.005
Early repolarization is a common electrocardiographic finding in acute pancreatitis and correlates with disease severity.
May aid severity assessment in acute pancreatitis; hypothesis-generating and requires validation before clinical adoption.
BACKGROUND/AIMS: Acute pancreatitis is a systemic disease with high mortality. The most common electrocardiography finding in acute pancreatitis cases is reported to be nonspecific repolarization changes in the literature. Recently, it is reported that repolarization changes carry high mortality risk. In this study, we aimed to investigate the association between repolarization changes and prognosis in acute pancreatitis cases. METHODS: Patients with acute pancreatitis referred to gastroenterohepatology clinic between 2009 and 2010 were included into the study. Echocardiography, electrocardiography, chest graph, abdominal sonography and/or computerized tomography, Ranson's and Glasgow's parameters and routine biochemistry tests of all patients were evaluated. RESULTS: A total of 55 cases [F/M: 22 (40%) / 33 (60%)] were included into the study. Thirty-nine of acute pancreatitis cases (70%) had electrocardiography changes. Electrocardiography changes were seen most frequently in cases with biliary (73%) and alcohol dependant pancreatitis cases (21%). The most frequently seen electrocardiographic finding was lateral early repolarization. There was a significant correlation between lateral early repolarization and Ranson score (p = 0.005). CONCLUSION: Early repolarization is the most common electrocardiographic findings and consistent with severity of acute pancreatitis cases.
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Sökmen et al. (2011) conducted an observational in Acute pancreatitis (n=55). Lateral early repolarization was evaluated on Correlation between lateral early repolarization and Ranson score (p=0.005). Lateral early repolarization was the most frequent electrocardiographic finding in acute pancreatitis and significantly correlated with disease severity as measured by the Ranson score (p = 0.005).
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