Key result
A greater change in Drug Burden Index (ΔDBI ≥0.09) during hospitalization was associated with higher 30-day readmission rates among older in-hospital fallers (IRR 2.02; 95% CI 1.49-2.74).
Why the study?
A higher drug burden index is associated with pre-admission falls leading to hospitalization, but its relationship with readmissions among in-hospital fallers was unclear.
Does a greater change in drug burden index during hospitalization increase 30-day readmission rates in older in-hospital fallers?
Cohort (n=113)
Does a greater change in drug burden index during hospitalization increase 30-day readmission rates in older in-hospital fallers?
Relative Risk: 2.02 (95% CI 1.49–2.74)
An increase in the drug burden index during hospitalization is associated with a doubled risk of 30-day readmission among older patients who experience in-hospital falls.
ΔDBI increase during hospitalization may flag higher readmission risk in older fallers; hypothesis-generating and requires prospective trials before guiding practice.
A higher drug burden index (DBI) is known to be associated with pre-admission falls leading to hospitalization. We investigated whether a mean difference in DBI (ΔDBI) between the events of in-hospital falls and hospital admission was associated with 30-day readmission in 113 patients ≥50 years who fell during their hospital stays between 2007 and 2014. A greater ΔDBI (≥0.09) was positively associated with higher 30-day readmission rates (incident rate ratio: 2.02; 95% confidence interval: 1.49-2.74). An effort to keep DBI low may thus decrease 30-day readmissions for older in-hospital fallers.
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Rasu et al. (2020) conducted a cohort in In-hospital falls (n=113). Greater change in Drug Burden Index (ΔDBI ≥0.09) vs. Lower change in Drug Burden Index (ΔDBI <0.09) was evaluated on 30-day readmission (IRR 2.02, 95% CI 1.49-2.74). A greater change in Drug Burden Index (ΔDBI ≥0.09) during hospitalization was associated with higher 30-day readmission rates among older in-hospital fallers (IRR 2.02; 95% CI 1.49-2.74).
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