Key result
18F-FDG PET/CT demonstrated a large filling defect with high FDG uptake from the left brachiocephalic vein to the superior vena cava, indicating a malignant tumor thrombus.
Case Report (n=1)
18F-FDG PET/CT can effectively identify intravenous tumor thrombus in patients with papillary thyroid carcinoma presenting with elevated thyroglobulin levels.
May aid FDG-PET/CT detection of tumor thrombus in PTC; hypothesis-generating and requires prospective validation.
A 24-year-old man with papillary thyroid carcinoma underwent 131I ablation after thyroidectomy. On posttherapy whole-body scintigraphy, only the remnant thyroid was visualized. In view of elevated unstimulated thyroglobulin level 7 months after 131I ablation, 18F-FDG PET/CT scan was ordered for further evaluation. On PET/CT images, a large filling defect from the dilated left brachiocephalic vein to superior vena cava was noted corresponding with high FDG uptake. It was considered as a malignant thrombus.
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Wang et al. (2022) conducted a case report in Papillary thyroid carcinoma (n=1). 18F-FDG PET/CT was evaluated on Detection of malignant thrombus. 18F-FDG PET/CT demonstrated a large filling defect with high FDG uptake from the left brachiocephalic vein to the superior vena cava, indicating a malignant tumor thrombus.
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