Key result
Blue light photoplethysmography provided heartbeat interval estimation accuracy nearly equivalent to green light photoplethysmography across different characteristic points and temperature conditions.
Why the study?
Previous studies evaluating blue light photoplethysmography (PPG) were biased by photodetectors with lower sensitivity to blue, despite hemoglobin absorption peaking in the blue spectrum and potential applications in monitoring during phototherapy.
Does blue light PPG provide accurate heartbeat interval estimation compared to green light PPG?
Does blue light PPG provide accurate heartbeat interval estimation compared to green light PPG?
Blue light PPG provides heartbeat interval estimation accuracy equivalent to green light PPG, suggesting it can be used for cardiovascular parameter acquisition.
Blue PPG may enable equivalent HBI estimation in wearables; hypothesis-generating and requires prospective validation before clinical adoption.
Since photoplethysmography (PPG) sensors are usually placed on open skin areas, temperature interference can be an issue. Currently, green light is the most widely used in the reflectance PPG for its relatively low artifact susceptibility. However, it has been known that hemoglobin absorption peaks at the blue part of the spectrum. Despite this fact, blue light has received little attention in the PPG field. Blue wavelengths are commonly used in phototherapy. Combining blue light-based treatments with simultaneous blue PPG acquisition could be potentially used in patients monitoring and studying the biological effects of light. Previous studies examining the PPG in blue light compared to other wavelengths employed photodetectors with inherently lower sensitivity to blue, thereby biasing the results. The present study assessed the accuracy of heartbeat intervals (HBIs) estimation from blue and green PPG signals, acquired under baseline and cold temperature conditions. Our PPG system is based on TCS3472 Color Sensor with equal sensitivity to both parts of the light spectrum to ensure unbiased comparison. The accuracy of the HBIs estimates, calculated with five characteristic points (PPG systolic peak, maximum of the first PPG derivative, maximum of the second PPG derivative, minimum of the second PPG derivative, and intersecting tangents) on both PPG signal types, was evaluated based on the electrocardiographic values. The statistical analyses demonstrated that in all cases, the HBIs estimation accuracy of blue PPG was nearly equivalent to the G PPG irrespective of the characteristic point and measurement condition. Therefore, blue PPG can be used for cardiovascular parameter acquisition. This paper is an extension of work originally presented at the 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
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Shchelkanova et al. (2021) studied this question. Blue light photoplethysmography (PPG) vs. Green light PPG was evaluated on Accuracy of heartbeat intervals (HBIs) estimation compared to electrocardiographic values. Blue light photoplethysmography provided heartbeat interval estimation accuracy nearly equivalent to green light photoplethysmography across different characteristic points and temperature conditions.
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