Key result
Transient left ventricular apical ballooning was diagnosed in 2% of patients referred for primary percutaneous intervention, representing a 6% incidence among female patients.
Why the study?
What is the prevalence of left ventricular apical ballooning syndrome in patients referred for primary percutaneous intervention?
Observational (n=638)
No
What is the prevalence of left ventricular apical ballooning syndrome in patients referred for primary percutaneous intervention?
Left ventricular apical ballooning syndrome (Takotsubo cardiomyopathy) is not uncommon, occurring in 2% of all patients and 6% of women presenting with acute myocardial infarction referred for primary PCI.
Answers are grounded in this paper and cite their sources.
Supports differential diagnosis of Takotsubo in women referred for primary PCI; leaves open prospective validation and outcome impact.
BACKGROUND: Left ventricular apical ballooning, a new syndrome recently described in Japan, is characterized by chest pain, electrocardiographic changes mimicking acute myocardial infarction, and transient apical dyskinesia with normal coronary arteries. Although several studies have defined the clinical characteristics, the prevalence of this syndrome remains unclear. HYPOTHESIS: This study sought to determine the prevalence of left ventricular apical ballooning syndrome. METHODS: From January 2002 to September 2004, clinical, echocardiographic, and angiographic data of hospitalization and follow-up were collected from 638 consecutive patients referred to our Heart Institute for primary percutaneous intervention. RESULTS: Thirteen patients (2%) were diagnosed with transient left ventricular apical ballooning. All but one patient were women, representing a 6% incidence for the female patients with acute myocardial infarction. A triggering factor was identified in eight. One patient died of cardiogenic shock. Left ventricular systolic function recovered completely within 4-5 weeks in the remaining 12 survivors. CONCLUSION: This syndrome is not uncommon and should be considered particularly in female patients presenting with acute myocardial infarction.
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Elian et al. (2006) conducted an observational in Acute myocardial infarction (n=638). Acute myocardial infarction was evaluated on Prevalence of left ventricular apical ballooning. Transient left ventricular apical ballooning was diagnosed in 2% of patients referred for primary percutaneous intervention, representing a 6% incidence among female patients.
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