A simple method for reliably demonstrating the growth depression activity of interferon preparations in monolayer cultures is described. Using this method interferon preparations from normal human leukocytes was found to be relatively more active in inhibiting the growth of heteroploid HeLa cells than diploid HESM cells. The antiviral factor of the preparations was, however, 6-7 times more active in HESM cells.
No takes yet. Share an insight, caveat, or question.
Lee et al. (1972) studied this question.