Poly(N-vinylimidazole) (PVIm), as a biocompatible, efficient, halogen-free, and reusable catalyst, was applied for the solvent-free synthesis of a library of bis(3-indolyl)methanes. The reaction was smoothly carried out under mild conditions, and the crude products were purified easily, and the pure products were obtained in high to excellent yields.
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Gorjian et al. (2021) studied this question.
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