Key result
Spontaneous normalization of negative T waves predicted ischemic or viable myocardial segments compared to persistent negative T waves (78% vs 33%, p=0.013).
Why the study?
Does spontaneous normalization of negative T waves predict myocardial viability in patients in the chronic stage of Q wave anterior MI?
Cohort (n=35)
Does spontaneous normalization of negative T waves predict myocardial viability in patients in the chronic stage of Q wave anterior MI?
Absolute Event Rate: 78% vs 33%
p-value: p=0.013
Spontaneous normalization of negative T waves on infarct-related ECG leads is a useful marker of residual myocardial viability in the chronic stage of Q wave anterior MI.
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May identify viable segments in chronic anterior MI; hypothesis-generating and requires prospective validation before clinical use.
Altun et al. (2004) conducted a cohort in Chronic phase of Q wave anterior myocardial infarction (n=35). Spontaneous normalization of negative T waves (TWN) vs. Presence of negative T waves was evaluated on Ischemic or viable myocardial segments on scintigraphic examination (p=0.013). Spontaneous normalization of negative T waves predicted ischemic or viable myocardial segments compared to persistent negative T waves (78% vs 33%, p=0.013).
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