Spontaneous Malformations in Laboratory Animals: Frequency of External, Internal and Skeletal Malformations in Rats, Rabbits and Mice*

of the Japanese Teratology Society requested Non-Clinical Evaluation Subcommittee (Chairman. Kazunaga Fukawa) of Japan Pharmaceutical Manufacturers Association (JPMA) to collect and edit the background data and then publish them in "Congenital Anomalies" as one of the commemorative activities of the 25th anniversary of the Japanese Teratology Society. The Non-Clinical Evaluation Subcommittee has organized a team for investigation and has asked the investigation to the pharmaceutical companies belonging t o JPMA and contract laboratories. Editing of the data has been conducted under the guidance by the editorial section of "Congenital Anomalies".