Key result
Disulfiram exposure in a patient with alcohol abuse induced catatonia, which fully remitted following electroconvulsive therapy.
Case Report (n=1)
Disulfiram can rarely induce catatonia, which may be successfully treated with electroconvulsive therapy.
Disulfiram may rarely trigger catatonia in alcohol use disorder; this Level 5 case leaves open ECT efficacy for prospective confirmation.
A case of catatonia induced by disulfiram Although catatonia has predominantly been evaluated as a subtype of schizophrenia, many of general medical conditions, some of neurological diseases or medications may cause catatonia. Disulfiram is an agent that is being used in the treatment of alcohol dependency by its aversive effect. It may cause neuropsychiatric side effects such as psychosis or delirium. Catatonic sydrome is a rare side effect of disulfiram. This paper aimed to report a case turning into catatonic syndrome following cognitive deterioration. The patient had no prior psychiatric history except alcohol abuse and was using disulfiram in the last month. With the diagnosis of “catatonia induced by disulfiram”, electroconvulsive therapy was applied. Full remission was obtained and the patient have been followed up without any medication. Concept of catatonia is discussed in this context.
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Balaban et al. (2010) conducted a case report in Catatonia (n=1). Disulfiram was evaluated on Development of catatonia and response to electroconvulsive therapy. Disulfiram exposure in a patient with alcohol abuse induced catatonia, which fully remitted following electroconvulsive therapy.
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