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Experimental evidence is presented showing that progressive renal ischaemic damage results in an increase in intracellular water with eventual production of the ‘no reflow’ phenomenon. Preservation techniques have been compared in their ability to resist intracellular water gain. A colloidal perfusate with low lipid content and a potassium concentration of greater than 15 mEqll was the most effective preservation medium tested.
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McLoughlin et al. (1974) studied this question.
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