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October 1, 1994Antimicrobial Agents and Chemotherapy

Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs

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Authors

AFAchraf Al FarajAmerican University of Iraq SulaimaniLALuigi A. AgrofoglioUniversité d'OrléansJWJohn WakefieldUniversity of Alabama at Birmingham

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Faraj et al. (1994) studied this question.

synapsesocial.com/papers/6a95c9e26c50c09bcf86a41bhttps://doi.org/10.1128/aac.38.10.2300
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase1993 · 31 citations
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  3. 3Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor1992 · 1,917 citations
  4. 4Biochemical pharmacology of (+)- and (-)-2',3'-dideoxy-3'-thiacytidine as anti-hepatitis B virus agents.1992 · 199 citations
  5. 5Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides1993 · 368 citations