Key result
Electroconvulsive therapy in a patient with an unsecured cerebral aneurysm associated with a high (14.5%) 5-year cumulative rupture rate resulted in a fatal aneurysmal subarachnoid hemorrhage.
Why the study?
There remains uncertainty regarding the safety of electroconvulsive therapy in patients with cerebral aneurysms.
Is electroconvulsive therapy safe in patients with unsecured cerebral aneurysms with a high rupture rate?
Case Report (n=1)
Is electroconvulsive therapy safe in patients with unsecured cerebral aneurysms with a high rupture rate?
Electroconvulsive therapy carries a risk of fatal subarachnoid hemorrhage in patients with unsecured cerebral aneurysms that have a high 5-year cumulative rupture rate.
ECT may warrant avoidance in high-rupture-rate unsecured aneurysms; leaves open safety across broader populations.
OBJECTIVES: The aim of the study was to report a case of a patient who experienced a fatal aneurysmal subarachnoid hemorrhage during the course of electroconvulsive therapy (ECT). METHODS: This is a case report and review of the literature. RESULTS: Electroconvulsive therapy is widely viewed as a safe and effective treatment for major depressive disorder; however, there remains some uncertainty regarding the safety of ECT in patients with cerebral aneurysms. Many cases exist documenting the safety of ECT in patients with both secured and unsecured cerebral aneurysms; however, these patients had aneurysms that were associated with a low (ie, ≤2.6%) 5-year cumulative rupture rate, whereas the patient in our case had an aneurysm associated with a 14.5% five-year cumulative rupture rate. CONCLUSIONS: We stress that ECT should not be viewed as a universally safe procedure in patients with cerebral aneurysms and the 5-year cumulative aneurysm rupture rate should be used in the discussion of the risk-benefit ratio of ECT in patients with unsecured cerebral aneurysms.
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Gugger et al. (2019) conducted a case report in Major depressive disorder with unsecured cerebral aneurysm (n=1). Electroconvulsive therapy (ECT) was evaluated on Fatal aneurysmal subarachnoid hemorrhage. Electroconvulsive therapy in a patient with an unsecured cerebral aneurysm associated with a high (14.5%) 5-year cumulative rupture rate resulted in a fatal aneurysmal subarachnoid hemorrhage.
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