Key result
Transcatheter left atrial appendage closure with the Watchman device offers favorable stroke risk reduction compared to warfarin in atrial fibrillation, though procedural complications are not infrequent.
Why the study?
Does transcatheter left atrial appendage closure with the Watchman device safely prevent stroke compared to warfarin in patients with atrial fibrillation?
Does transcatheter left atrial appendage closure with the Watchman device safely prevent stroke compared to warfarin in patients with atrial fibrillation?
Understanding and managing procedural complications of LAA closure with the Watchman device is essential to optimize its safety and efficacy for stroke prevention in atrial fibrillation.
Warrants vigilance for procedural risks with Watchman; leaves open optimal role versus contemporary anticoagulants in AF.
Transcatheter closure of the left atrial appendage has been developed as an alternative to chronic oral anticoagulation for stroke prevention in patients with atrial fibrillation, and as a primary therapy for patients with contraindications to chronic oral anticoagulation. The promise of this new intervention compared with warfarin has been supported by several, small studies and two pivotal randomized trial with the Watchman Device. The results regarding risk reduction for stroke have been favourable although acute complications were not infrequent. Procedural complications, which are mainly related to transseptal puncture and device implantation, include air embolism, pericardial effusions/tamponade and device embolization. Knowledge of nature, management and prevention of complications should minimize the risk of complications and allow transcatheter left atrial appendage closure to emerge as a therapeutic option for patients with atrial fibrillation at risk for cardioembolic stroke.
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Sven Möbius‐Winkler (2015) conducted a review in Atrial fibrillation. Transcatheter left atrial appendage closure (Watchman Device) vs. Chronic oral anticoagulation (warfarin) was evaluated. Transcatheter left atrial appendage closure with the Watchman device offers favorable stroke risk reduction compared to warfarin in atrial fibrillation, though procedural complications are not infrequent.
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