Key result
Anesthesia with pentobarbital sodium exaggerated the cardiovascular reflex response to passive muscle stretch, increasing HR by 14 beats/min and MAP by 14 mmHg compared to the conscious condition.
Authors
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Anesthesia with pentobarbital may overestimate reflex responses in experimental models; leaves open translation to conscious states or alternative anesthetics.
Matsukawa et al. (2007) studied this question. Anesthesia (pentobarbital sodium) vs. Conscious condition was evaluated on Heart rate (HR) and mean arterial blood pressure (MAP) changes during passive stretch. Anesthesia with pentobarbital sodium exaggerated the cardiovascular reflex response to passive muscle stretch, increasing HR by 14 beats/min and MAP by 14 mmHg compared to the conscious condition.
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