Key result
Salvage surgery following preoperative transcatheter arterial embolization successfully treated a giant primary pulmonary leiomyosarcoma, with no local recurrence at 3 months.
Why the study?
Primary pulmonary leiomyosarcomas are rare, aggressive tumors that are frequently misdiagnosed due to nonspecific symptoms, and require timely, radical surgical intervention.
Case Report (n=1)
No
Preoperative transcatheter arterial embolization followed by salvage surgery via sterno-thoracotomy is a feasible and effective treatment for giant primary pulmonary leiomyosarcomas with abnormal angiogenesis.
Supports feasibility of embolization plus salvage surgery for rare giant pulmonary leiomyosarcoma; hypothesis-generating and requires validation in larger series.
Primary pulmonary leiomyosarcomas (PPLs) are incredibly rare tumors, characterized by an often-aggressive clinical behavior. Diagnosis is frequently incidental. Whenever present, symptoms are nonspecific, thus PPLs are usually misdiagnosed as other more common respiratory diseases or lung cancer subtypes. Surgery is the best treatment choice and in the therapeutic strategy, timeliness and radicality are of major importance. We report the case of a huge left PPL, successfully treated with salvage surgery after a careful multidisciplinary preoperative assessment, which permitted a prompt diagnostic path and surgery.
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Sicolo et al. (2022) conducted a case report in Primary pulmonary leiomyosarcoma (n=1). Salvage surgery (intrapericardial left pneumonectomy with radical en-bloc mass resection) was evaluated on Surgical success and postoperative recovery. Salvage surgery following preoperative transcatheter arterial embolization successfully treated a giant primary pulmonary leiomyosarcoma, with no local recurrence at 3 months.
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