A treatment-resistant manic patient failed to respond to conventional treatment, adjunctive olanzapine (20 mg/day), clozapine (600 mg/day), or ECT alone, but did respond to ECT combined with low dose clozapine (200 mg/day). Maintenance ECT combined with clozapine resulted in a remission over the 18-month period.
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Worrawat Chanpattana (2000) studied this question.
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